Product ID:1,4-DIOXANE, D-111
MSDS Date:06/27/1988
FSC:6810
NIIN:00-050-3430
MSDS Number: CDWZD

OCCUPATIONAL HEALTH SERVICES INC

450 7TH AVE SUITE 2407
NEW YORK, NY 10123
US

Emergency Phone: 615-292-1180

Info Phone: 212-967-1100

Cage: DO501

OCCUPATIONAL HEALTH SERVICES INC

NEW YORK, NY 10036 US

Telephone: 212-789-3535

Cage: 0G9K0

P-DIOXANE; (1,4-DIOXANE) (SARA 313) (CERCLA)

CAS: 123-91-1

RTECS: JG8225000

Fraction By Weight: 100%

OSHA PEL 100 PPM, S

ACGIH TLV: 25 PPM, S

EPA Report Quantity: 100 LBS

DOT Report Quantity: 100 LBS

FLOODING AMTS AS FOG, SOLID STREAMS MAY NOT BE

RTECS: 9999999ZZ

FAR A DIST AS POSS. AVOID BRTHG TOX VAPS, KEEP

RTECS: 9999999ZZ

FIGHT FIRE. USE WATER TO KEEP FIRE-EXPOS CNTNRS

RTECS: 9999999ZZ

DISPERSE VAPS & PROTECT PERS ATTEMPTING TO STOP

RTECS: 9999999ZZ

EXPOS & TO DILUTE SPILLS TO NONFLAM MIXS. WATER MAY

RTECS: 9999999ZZ

VAPS MAY CAUSE

RTECS: 9999999ZZ

NO HUMAN DATA AVAIL. LG DOSES

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AUTOPSY REVEALED HEMORR AREAS IN PYLORIC REGION OF

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ENLARGED KIDNEYS. ASPIR MAY RSLT IN PNEUM. CHRONIC

RTECS: 9999999ZZ

NAUS & VOMIT, PAIN & TENDERNESS IN ABDOMEN & LUMBAR

RTECS: 9999999ZZ

FROM ACUTE RENAL FAILURE. AUTOPSIES SHOWED LUNG &

RTECS: 9999999ZZ

NEPHRITIS & NECROSIS, LEUKOCYTOSIS & BRONCHOPNEUM.

RTECS: 9999999ZZ

HAVE CONTRIBUTED TO DEATH OF WORKER AFTER 1 WK

RTECS: 9999999ZZ

LIVER & KIDNEY DMG. TUMOR PROMOTER ACTIVITY IN MICE

RTECS: 9999999ZZ

LIVER & KIDNEY DMG, ULCERATION OF STOM, HEPATOMAS,

RTECS: 9999999ZZ

LYMPHOSARCOMA, CHOLANGIOMAS & GALL BLADDER

RTECS: 9999999ZZ

IMMED W/LG AMTS OF WATER OCCASNLY LIFT UPPER &

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REMOVE BY GASTRIC

RTECS: 9999999ZZ

GASTRIC LAVAGE/EMESIS IF UNCON. MAINTAIN BLOOD

RTECS: 9999999ZZ

KEEP

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LAVAGE. O*2 & LAVAGE SHOULD BE ADMIN BY QUALIFIED

RTECS: 9999999ZZ

HAZ AREA! KEEP UNNEC PEOPLE AWAY; ISOLATE AREA

RTECS: 9999999ZZ

ACT (PROPOSITION 65) PROHIBITS CONTAM ANY KNOWN

RTECS: 9999999ZZ

ISOLATE FROM COMBUST/OXIDIZING MATLS &

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LD50 LC50 Mixture:NONE SPECIFIED BY MANUFACTURER.
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:YES IARC:YES OSHA:NO
Health Hazards Acute and Chronic:ACUTE: INHAL:NOSE, THORAT & RESP TRACT
IRRIT. CMPD HAS POOR WARNING PROPERTIES & CAN BE INHALED IN AMTS
THAT MAY CAUSE SERIOUS SYSTEMIC INJURY. SYMPS OF SYSTEMIC TOX INCL
HDCH, VERTIGO, DROW, DYSPNEA, NAUS & VOMIT, OLIGURIA, ANURIA,
HEPATOMEGALY & SEV LIVER & KIDNEY DMG. INHAL CAUSE INCRD
SALIVATION, (EFTS OF OVEREXP)
Explanation of Carcinogenicity:P-DIOXANE:IARC MONOGRAPHS, SUPP, VOL 7,
PG 201. 1987:GROUP 2B. NTP 7TH ANNUAL RPT ON CARCINS, 1994:ANTIC TO
BE CARCIN.
Effects of Overexposure:HLTH HAZ:LACRIM, NARCOS & BEHAVIOR CHGS IN
ANIMALS. AUTOPSY SHOWED LUNG, LIVER & KIDNEY DMG, CONGESTION &
EDEMA OF LUNGS & INCRD BLOOD COUNTS. SKIN:IRRIT W/REDNESS & PAIN.
ALLERGIC CNTCT DERM REPORTED . SKIN ABSORPTION MAY OCCUR W/HDCH,
NAUS & VOMIT; PRDCED SIGNS OF UNSTEADINESS, INCOORD, NARCOS,
ERYTHEMA & LIVER(ING 7)
Medical Cond Aggravated by Exposure:PERSONS WITH PREEXISTING LIVER,
KIDNEY, PULMONARY OR SKIN DISORDERS MAY BE AT AN INCREASED RISK
FROM EXPOSURE.

First Aid:INHAL:REMOVE TO FRESH AIR IMMED. IF BRTHG HAS STOPPED GIVE
ARTF RESP. MAINTAIN AIRWAY & BLOOD PRESS & ADMIN O*2 IF AVAIL. KEEP
WARM & AT REST. ADMIN OF O*2 SHOULD BE PERFORMED BY QUALIFIED PERS.
GET M ED ATTN IMMED. SKIN: REMOVE CONTAMD CLTHG & SHOES IMMED. WASH
AREA W/SOAP OR MILD DETERGENT & LG AMTS OF WATER UNTIL NO EVID OF
CHEM REMAINS (APPROX 15-20 MIN). GET MED ATTN IMMED. EYE: WASH (ING
18)

Flash Point Method:CC
Flash Point:54.0F,12.2C
Lower Limits:2.0%
Upper Limits:22%
Extinguishing Media:DRY CHEMICAL, CARBON DIOXIDE, HALON, WATER SPRAY OR
ALCOHOL FOAM. FOR LARGER FIRES USE WATER SPRAY, FOG OR ALCOHOL
FOAM.
Fire Fighting Procedures:NIOSH APPRVD SCBA & FULL PROT EQUIP . MOVE
CNTNR FROM FIRE AREA IF POSS. COOL FIRE-EXPOS CNTNRS W/WATER FROM
SIDE UNTIL WELL AFTER FIRE IS OUT. (SUPDAT)
Unusual Fire/Explosion Hazard:DANGEROUS FIRE HAZ & MOD EXPLO HAZ WHEN
EXPOS TO HEAT/FLAME. VAP-AIR MIXS EXPLO. VAPS ARE HVR/AIR & MAY
TRAVEL CONSIDERABLE DIST TO IGNIT SOURCE & FLASH BACK.

Spill Release Procedures:SHUT OFF IGNIT SOURCES. STOP LEAK IF W/OUT
RISK. USE WATER SPRAY TO REDUCE VAPS. SM SPILLS:TAKE UP
W/SAND/OTHER ABSORB MATL & PLACE INTO CNTNRS FOR LATER DISP. LG
SPILLS:DIKE FAR AHEAD OF SPILL FOR LA TER DISP. NO SMKNG, FLAMES OR
FLARES IN(ING 23)
Neutralizing Agent:NONE SPECIFIED BY MANUFACTURER.

Handling and Storage Precautions:STORE I/A/W 29 CFR 1910.106. PROTECT
AGAINST PHYSICAL DMG. OUTSIDE/DETACHED STOR PREF. INSIDE STOR
SHOULD BE IN STD FLAM LIQ STOR ROOM/CLOSET.(ING 25)
Other Precautions:SUBSTANCES WITH LOW ELECTROCONDUCTIVITY, WHICH MAY BE
IGNITED BY ELECTROSTATIC SPARKS, SHOULD BE STORED IN CONTAINERS
WHICH MEET BONDING & GROUNDING GUIDELINES SPECIFIED IN NFPA
77-1983, RECOMMENDED P RACTICE ON STATIC ELECTRICITY.

Respiratory Protection:USE NIOSH APPRVD RESPS. AT ANY CONC:SCBA W/FULL
FCPCE OPER IN PRESS-DEMAND/OTHER POS PRESS MODE. SUPPLIED AIR RESP
W/FULL FCPCE OPER IN PRESS DEMAND/OTHER POS PRESS MODE IN COMBO
W/AUXILIARY SCBA OPER IN PRESS DEMAND/OTHER POS PRESS MODE.
Ventilation:PROVIDE LOCAL EXHAUST OR PROCESS ENCLOSURE VENT TO MEET
PUBLISHED EXPOSURE LIMITS. VENT EQUIP MUST BE EXPLOSION-PROOF.
Protective Gloves:IMPERVIOUS GLOVES .
Eye Protection:ANSI APPRVD CHEM WORKERS GOGGLES .
Other Protective Equipment:ANSI APPROVED EYE WASH & DELUGE SHOWER .
APPROP PROT (IMPERVIOUS) CLTHG & EQUIP TO PVNT RPTD/PRLNGD SKIN
CONTACT.
Work Hygienic Practices:CONTACT LENSES SHOULD NOT BE WORN.
Supplemental Safety and Health
FIRE FIGHT PROC:STAY AWAY FROM STOR TANK ENDS. FOR MASSIVE FIRE IN STOR
AREA, USE UNMANNED HOSE HOLDER/MONITOR NOZZS, ELSE W/DRAW FROM AREA
& LET FIRE BURN. W/DRAW IMMED IN CASE OF RISING SOUND FROM V ENTING
SFTY DEVICE/ANY DISCOLORATION OFSTOR TANK DUE TO FIRE. EXTING ONLY
IF FLOW CAN BE STOPPED, USE WATER IN (ING 2)

Boiling Pt:B.P. Text:214F,101C
Melt/Freeze Pt:M.P/F.P Text:53.0F,11.7C
Vapor Pres:27 @ 20C
Vapor Density:3.0
Spec Gravity:1.034
Evaporation Rate & Reference:2.7 (BUTYL ACETATE=1)
Solubility in Water:SOLUBLE
Appearance and Odor:COLORLESS LIQUID WITH A FAINT ETHER-LIKE ODOR.

Stability Indicator/Materials to Avoid:YES
NICKEL (RANEY)+HYDROGEN; OXIDIZERS(STRONG); SILVER PERCHLORATE. CNTCT
NEHC FOR COMPLETE LIST OF MATLS TO AVOID .
Stability Condition to Avoid:FORMS PEROXIDES ON STANDING, ESP WHEN
CONTAMD W/MOISTURE. IF DISTILLED OR EVAPORATED TO DRYNESS, AN
EXPLOSION MAY OCCUR.
Hazardous Decomposition Products:THERMAL DECOMPOSITION PRODUCTS MAY
INCLUDE TOXIC OXIDES OF CARBON.

Waste Disposal Methods:OBSERVE ALL FEDERAL, STATE AND LOCAL REGULATIONS
WHEN STORING OR DISPOSING OF THIS SUBSTANCE.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.